Olga Baidukova
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Room: 410 Email: baidukol@hu-berlin.de Tel: (030) 2093 98278 |
The unicellar green algae, Chlamydomonas reinhardtii, can orient themselves under various light conditions. They swim toward or away from light under continuous illumination (phototaxis) or exhibit photophobic or stop response when the light intensity changes abruptly. This behaviour is mediated by a photosensing system including light-gated ion channels, channelrhodopsins (ChRs), as primary photoreceptors. Less well-studied voltage-gated calcium channels (VGCCs) are also believed to be involved in the control of motion reactions in the green algae. My research interest lies in the biophysical study of motility behaviour of Chlamydomonas with the focus on the function of ChRs and VGCCs. The methods used in my work are light scattering, single-cells tracking, high-resolution microscopy and computed tomography.
Baidukova O., Oppermann J., Kelterborn S., Fernandez Lahore R.G., Schumacher D., Evers H., Kamrani Y.Y. and Hegemann P. (2022) Gating and ion selectivity of Channelrhodopsins are critical for photo-activated orientation of Chlamydomonas as shown by in vivo point mutation. Nat. Commun. 13, 7253. https://doi.org/10.1038/s41467-022-35018-6
Catalan R.E., Fragkopulos A.A., von Trott N., Kelterborn S., Baidukova O., Hegemann P., Bäumchen O. (2023) Light regulated adsorption and desorption of Chlamydomonas cells at surfaces. Soft Matter 19, 306 - 314. https://doi.org/10.1039/D2SM01039A
Baidukova O., Kelterborn S., Sizova I. and Hegemann P. (2022) Reverse Genetics. Chapter 17 In: Goodenough U. (eds) The Chlamydomonas Sourcebook. Volume 1: Introduction to Chlamydomonas and Its Laboratory, Academic Press, Cambridge, USA.
Kelterborn S., Boehning F., Sizova I., Baidukova O., Evers H. and Hegemann P. (2022) Gene Editing in Green Alga Chlamydomonas reinhardtii via CRISPR-Cas9 Ribonucleoproteins. In: Zubringen M.D. (eds) Plant Synthetic Biology. Methods in Molecular Biology, Vol 2379. Humana, New York, NY.