Direkt zum InhaltDirekt zur SucheDirekt zur Navigation
▼ Zielgruppen ▼
 

Humboldt-Universitaet zu Berlin - Structural Biology / Biochemistry

Humboldt-Universitaet zu Berlin | Department of Biology | Structural Biology / Biochemistry | A catalytic active Michaelis-complex shows its secrets

A catalytic active Michaelis-complex shows its secrets

Our latest paper in Nature Communications describes how only authentic Michaelis complexes display a strong donor–acceptor complex between reduced flavin and substrate. This interaction likely activates the catalytic ground state of the reduced flavin, accelerating the reaction within a compressed cofactor–substrate complex.

http://www.nature.com/articles/ncomms16084