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Humboldt-Universität zu Berlin - Systems Immunology Lab

 Systems Immunology Lab


The Systems Immunology Lab focuses on basic and translational antibody research in academia-industry collaborations. It aims at exploitation of antibodies as both research and diagnostic tools. The Lab has also a leading role in a systems medicine approach to personalized immunosuppressive treatment following kidney transplantation (e:KID consortium), where it provides mathematical models and multi-omics bioinformatics data analysis to support medical decisions.

Examples of the Lab’s commitment include: i) the development of combined hard- and software tools for monitoring of antibody key features such as specificity, affinity, cross-reactivity and lot-to-lot consistency, and ii) the development of an all-in-one tool which bundles biomarker extraction, validation and clinical application of antibody signatures for diagnostics, monitoring and prognosis.

The Systems Immunology Lab also provides contract research and consulting services in the following areas:

  • Design and execution of antibody-based immunoassay applications (especially protein and peptides arrays, ELISA, flow cytometry)
  • Automated data analysis for antibody-based immunoassay applications
  • Biomarker extraction and validation strategies
  • Statistics, bioinformatics, and immuno-bioinformatics support for the analysis of experimental and clinical data




Dr. Michal Or-Guil
e-mail: michal.orguil@gmail.com, m.orguil@biologie.hu-berlin.de

Humboldt University Berlin

Department of Biology

Second affiliation:

Charité - Universtätsmedizin Berlin

Research Center ImmunoSciences (RCIS)



Philippstr. 11-13; Rhoda-Erdmann-Haus (Haus 22)
10115 Berlin

Phone: +49-30-2093-49666