Humboldt-Universität zu Berlin - Experimentelle Biophysik/Mechanobiologie (Juniorprofessur)

Morteza Aramesh



ETH Zürich
Department for Health Sciences and Technology
Laboratory of Applied Mechanobiology

Vladimir-Prelog-Weg 1-5/10

8093 Zürich




Tel: +41 44 633 75 23





I’m a postdoctoral researcher at Prof. Klotzsch’s group working on immunoengineering aspects of T-cell activation. I obtained my PhD degree in Physics and so far have developed multiple tools and methods to study bio-matter interfaces. I’m now interested in applying those tools to important biological applications such as immunotherapy in the context of T-cell activation. T-cell migration, activation and function are important aspects of immunotherapy and several studies have demonstrated that the microenvironment could strongly influence T-cell response. I’m implementing nanotechnology-based approaches to engineer T-cell response towards more efficient activation and expansion. Recent studies in our group has demonstrated that mechanical forces have an impact on dynamics of the sub-cellular system, and may be a critical parameter in T-cell activation too. However, the mechanobiological pathways of T-cell activations is not yet fully understood. In our project we aim to monitor the activity of T-cells as a functional mechanical forces. We study the structural and molecular (genetics) response of the cell to the applied forces. Our powerful tool to study the cellular structure is Super Resolution Microscopy, which allows us to resolve the nanostructure of the sub-cellular organization of proteins and DNA.


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M. Aramesh, Y. Mayamei, A. Wolff, and K. Ostrikov. “Superplastic Nanoscale Pore Shaping by Ion Irradiation.” Nature Communications, 2018, 9, 835. 
doi:10.1038/s41467-018-03316-7. Link (Open Access)


L. Dorwling-Carter, M. Aramesh, C. Forro, R. Tiefenauer, I. Shorubalko, J. Vörös, and T. Zambelli. “Simultaneous scanning ion conductance and atomic force microscopy with a nanopore: effect of the aperture edge on the ion current images.” Journal of Applied Physics, 2018, 124, 174902.


R.F. Tiefenauer, T. Dalgaty, T. Keplinger, T. Tian, C‐J. Shih, J. Vörös, and M. Aramesh. “Monolayer Graphene Coupled to a Flexible Plasmonic Nanograting for Ultrasensitive Strain Monitoring.” Small, 2018, 1801187.
doi: 10.1002/smll.201801187. Link (Publisher)


M. Aramesh, P.A. Tran, K. Ostrikov, and S. Prawer. “Conformal Nanocarbon Coating of Alumina Nanocrystals for Biosensing and Bioimaging.” Carbon, 2017, 122 422–27.
doi:10.1016/j.carbon.2017.06.101. Link (Publisher). Link (arXiv)


M. Aramesh, O. Shimoni, K. Ostrikov, S. Prawer, and J. Cervenka. “Surface Charge Effects in Protein Adsorption on Nanodiamonds.” Nanoscale, 2015, 7, 5726-5736.
doi:10.1039/c5nr00250h. Link (Publisher)


M. Aramesh, O. Shimoni, K. Fox, T.J. Karle, A. Lohrmann, K. Ostrikov, S. Prawer, and J. Cervenka. “Ultra-High-Density 3D DNA Arrays within Nanoporous Biocompatible Membranes for Single-Molecule-Level Detection and Purification of Circulating Nucleic Acids.” Nanoscale, 2015, 7, 5998-6006. (Cover page) 
doi:10.1039/c4nr07351g. Link (Publisher) . Link (Cover page)

The full publication list in Google Scholar.