Humboldt-Universität zu Berlin - Molecular Parasitology

New paper in Mol. Biol. Cell.

late endosomes are a focal point of lipid transport. NPC and LAMP proteins, which are required for cholesterol export from late endosomes, are necessary for effective Plasmodium berghei development.

Sequestration of cholesterol within the host late endocytic pathway restricts liver-stage Plasmodium development.

Petersen W, Stenzel W, Silvie O, Blanz J, Saftig P, Matuschewski K, Ingmundson A. Mol Biol Cell. 2017 Mar 15;28(6):726-735. PMID: 28122820