Hasan Simsek
Humboldt-Universität zu Berlin
Institut für Biophysik
Experimentelle Biophysik/Mechanobiologie
Invalidenstrasse 42
10115 Berlin
Tel: +49 30 2093 98284
E-mail: hasan.simsek@hu-berlin.de
I worked as a medical doctor and medical genetics specialist at Marmara University School of Medicine in Turkey. During this period, I became more interested in the diagnosis, treatment, and research of genetic diseases, especially neurodegenerative and immunological diseases. I am currently researching the effects of hydrostatic pressure on T cells as a postdoctoral Philipp Schwartz Initiative fellow in Prof. Klotzsch's lab. T cells are exposed to different levels of fluid pressure in different parts of our body. It has been shown in previous studies that these cells have different activation and differentiation states and that the fluid pressure in the tumor microenvironment has a negative effect on T cells. If the effect of fluid pressure on T cells and related mechanisms can be clarified, it would allow to finetune their behaviour towards adoptive immunotherapy.