Humboldt-Universität zu Berlin - Molekulare Zellbiologie/ Molecular Cell Biology


Selected publications:
Selected publications:
  • Bessler L, Kaur N, Vogt LM, Flemmich L, Winz ML, MIcura R, Ehrenhofer-Murray* and Helm M*. Functional integration of a semi-synthetic azido-queuosine derivative into translation and a tRNA modification circuit. Nucleic Acids Res. 2022 Oct 14;50(18):10785-10800.
  • Nguyen TMT, Munhoven A, Samel-Pommerencke A, Kshirsagar R, Cuomo A, Bonaldi T, Ehrenhofer-Murray AE. Methylation of CENP-A/Cse4 on arginine 143 and lysine 131 regulates kinetochore stability in yeast. Genetics. 2023 Feb 22:iyad028. doi: 10.1093/genetics/iyad028.
  • Shahnejat-Busheri S, Ehrenhofer-Murray AE. The ATAD2/ANCCA homolog YTA7 cooperates with Scm3HJURP  to deposit  Cse4CENP-A at the centromere in yeast. PNAS March10,2020 117(10) 5386-5393. 
  • Yan K, Yang J, Zhang Z, McLaughlin SH, Chang L, Fasci D, Ehrenhofer-Murray AE, Heck AJR, Barford D. Structure of the iiner kinetochore CCAN complex assembled onto a centromeric nucleosome. Nature 2019 Oct; 574(7777):278-282. 
  • Anedchenko EA, Samel-Pommerencke A, Tran Nguyen TM, Shahnejat-Bushehri S, Pöpsel J, Lauster D, Herrmann A, Rappsilber J, Cuomo A, Bonaldi T, Ehrenhofer-Murray AE. (2019) The kinetochore module Okp1CENP-Q/Ame1CENP-U is a reader for N-terminal modifications on the centromeric histone Cse4CENP-A. EMBO J. 2019 Jan 3;38(1). pii: e98991.
  • Müller M, Samel-Pommerencke A, Legrand C, Tuorto F, Lyko F, Ehrenhofer-Murray AE. (2019) Division of labour: tRNA methylation by the NSun2 tRNA methyltransferases Trm4a and Trm4b in fission yeast.RNA Biol. 2019 Jan 15.
  • Müller M, Hartmann M, Schuster I, Bender S, Thüring KL, Helm M, Katze JR, Nellen W, Lyko F, Ehrenhofer-Murray AE. (2015) Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine. Nucleic Acids Res. 2015 Dec 15;43(22):10952-62
  • Tuorto F, Legrand C, Cirzi C, Federico G, Liebers R, Müller M, Ehrenhofer-Murray AE, Dittmar G, Gröne HJ, Lyko F. (2018) Queuosine-modified tRNAs confer nutritional control of protein translation. EMBO J. 2018 Sep 14;37(18). pii: e99777.
  • Becker M, Müller S, Nellen W, Jurkowski TP, Jeltsch A, Ehrenhofer-Murray AE. (2012) Pmt1, a Dnmt2 homolog in Schizosaccharomyces pombe, mediates tRNA methylation in response to nutrient signaling. Nucleic Acids Res. 2012 Dec;40(22):11648-58.
  • Stephan J, Franke J, Ehrenhofer-Murray AE. (2013) Chemical genetic screen in fission yeast reveals roles for vacuolar acidification, mitochondrial fission, and cellular GMP levels in lifespan extension. Aging Cell 2013 Aug;12(4):574-83
  • Samel A., Cuomo A., Bonaldi T., A. E. Ehrenhofer-Murray. (2012) Methylation of CenH3 arginine 37 regulates kinetochore integrity and chromosome segregation. PNAS 109(23):9029-34
  • Ehrentraut, S. Hassler, M., Oppikofer, M., Kueng, S., Weber, J. M., Mueller, J. W., Gasser, S. M., Ladurner, A. G. and A. E. Ehrenhofer-Murray (2011) Structural basis for the role of the Sir3 AAA+ domain in silencing: Interaction with Sir4 and unmethylated histone H3K79. Genes Dev Sep 1, 2011; 25 (17), 1835-46
  • Ehrentraut S, Weber JM, Dybowski JN, Hoffmann D, Ehrenhofer-Murray AE (2010) Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrate. PNAS. 2010 Mar 23;107(12):5522-7.
  • Irlbacher H, Franke J, Manke T, Vingron M, Ehrenhofer-Murray AE (2005) Control of replication initiation and heterochromatin formation in Saccharomyces cerevisiae by a regulator of meiotic gene expression. Genes Dev. 2005 Aug 1;19(15):1811-22.