Humboldt-Universität zu Berlin - Molekulare Parasitologie

Publikationen

Publikationen der letzten 5 Jahre in referierten Zeitschriften
  • Stange J, Hepworth MR, Rausch S, Zajic L, Kühl AA, Uyttenhove C, Renauld JC, Hartmann S, Lucius R (2012) IL-22 mediates host defense against an intestinal intracellular parasite in the absence of IFN-y at the cost of Th17-driven immunopathology. J Immunol 188:2410-8.
  • Sampels V, Hartmann A, Dietrich I, Coppens I, Sheiner L, Striepen B, Herrmann A, Lucius R, Gupta N (2012) Conditional mutagenesis of a novel choline kinase demonstrates plasticity of phosphatidylcholine biolgenesis and gene expression in Toxoplasma gondii. J Biol Chem 287:16289-99.
  • Schmid M, Lehmann MJ, Lucius R, Gupta N (2012) Apicomplexan parasite, eimeria falciformis, co-opts host tryptophan catabolism for life cycle progression in mouse. J Biol Chem 287:20197-207.
  • Gupta N, Hartmann A, Lucius R, Voelker DR (2012) The obligate intracellular parasite Toxoplasma gondii secretes a soluble phospahtidylserine decarboxylase. J Biol Chem 287:22938-47.
  • Blume M, Hliscs M, Rodriguez-Contreras D, Sanchez M, Landfear S, Lucius R, Matuschewski K, Gupta N (2011) A constitutive pan-hexose permease for the Plasmodium life cycle and transgenic models for screening fo antimalarial sugar analogs. FASEB J 25:1218-29.
  • Klotz C, Ziegler T, Figueiredo AS, Rausch S, Hepworth MR, Obsivac N, Sers C, Lang R, Hammerstein P, Lucius R, Hartmann S (2011) A helminth immunomodulator exploits host signaling events to regulate cytokine production in macrophages. PLoS Pathog 7:e1001248.
  • Rausch S, Held J, Stange J, Lendner M, Hepworth MR, Klotz C, Lucius R, Pogonka T, Hartmann S (2010) A matter of timing: early, not chronic phase intestinal nematode infection restrains control of a concurrent enteric protozoan infection. Eur J Immunol 40:2804-15.
  • Struebing U, Lucius R, Heorauf A, Pfarr KM (2010) Mitochondrial genes for heme-dependent respiratory chain complexes are up-regulated after depletion of Wolbachia from filarial nematodes. Inf J Parasitol 40:1193-202.
  • Sereda MJ, Hartmann S, Büttner DW, Volkmer R, Hovestädt M, Brattig N, Lucius R (2010) Characterization of the allergen filarial tropomyosin with an invertebrate specific monoclonal antibody. Acta Trop: 116:61-7.
  • Pogonka T, Schelzke K, Stange J, Papadakis K, Steinfelder S, Liesenfeld O, Lucius R (2010) CD8+ cells protect mice against reinfection with the intestinal parasite Eimeria falciformis. Microbes Infect 12:218-26.
  • Rausch S, Hühn J, Kirchhoff D, Loddenkemper C, Hepworth MR, Klotz C, Sparwasser T, Hamann A, Lucius R, Hartmann S (2009) Establishment of nematode infection despite increased Th cell type 2 responses and immunopathology after selective depletion of Focp3+ cells. Eur J Immunol 99:1-12.
  • Blume M, Rodriguez-Contreras D, Landfear S, Fleige T, Soldati-Favre D, Lucius R, Gupta N (2009) Host-derived glucose is despensible for the obligate intracellular pathogen Toxoplasma gondii. Proc Natl Acad Sci USA 106:12998-13003.
  • Hartmann S, Schnöller C, Dahten A, Avagyan A, Rausch S, Lendner M, Bocian C, Pillai S, Lucius R, Worm M, Hamelmann E (2009) Gastrointestinal nematode infection interferes with experimental allergic airway inflammation but not atopic dermatitis. Clin Exp Allergy 39: 1585-96.
  • Kuhn C, Lucius R, Matthes HF, Meusel G, Reich B, Kalinna BH (2008) Characterisation of recombinant immunoreactive antigens of the scab mite Sarcoptes scabiei. Vet Parasitol 153:329-337.
  • Lendner M, Doligalska M, Lucius R, Hartmann S (2008) Attempts to establish RNA interference in Heligmosomoides polygyrus. Mol Biochem Parasitol 161:21-31.
  • Rzepecka J, Rausch S, Klotz C, Schnöller C, Kornprobst T, Hagen J, Ignatius R, Lucius R, Hartmann S (2008) Calreticulin from the intestinal nematode Heligmosomoides polygyrus is a Th2-skewing protein and interacts with murine scavenger receptor-A. Mol Immunol 46:1109-1119.
  • Rausch S, Hühn J, Kirchhoff D, Rzepecka J, Schnöller C, Pillai S, Loddenkemper C, Scheffold A, Hamann A, Lucius R, Hartmann S (2008) Functional analysis of effector and regulatory T cells in a parasitic nematode infection. Infection and Immunity, 76:1908-1919.
  • Schnöller C, Rausch S, Pillai S, Avagyan A, Wittig B, Loddenkemper C, Hamann A, Hamelmann E, Lucius R, Hartmann S (2008) A helminth immunomodulator reduces allergic and inflammatory responses by induction of IL-10 producing macrophages. J. Immunol. 180:4265-4272.
  • Sereda M, Hartmann S, Lucius R (2008). Helminths and allergy: The example of tropomyosin. Trends Parasitol. 24:272-278.
  • Tachu B, Pillai S, Lucius R, Pogonka T (2008) Essential role of chitinase in the development of the filarial nematode Acanthocheilonema viteae. Infection and Immunity 76: 221-228.
  • Knopf K, Madriles Helm A, Lucius R, Bleiss W, Taraschewski H (2008) Migratory response of the European Eel (Anguilla anguilla) leukocytes to the eel swimbladder nematode Anguillicola crassus. Parasitology Research, 102:1311-1316.
  • Knopf K, Lucius R (2008) Vaccination of eels (Anguilla japonica and Anguilla anguilla) against Anguillicola crassus with irradiated L3. Parasitology, 135:633-40.

 

Buchbeiträge, Übersichtsarbeiten
  • Müller N, Lucius R (2005) Antiparasitäre Impfstoffe. In: Allgemeine Parasitologie. Hrsg. T. Hiepe, R. Lucius, B. Gottstein. Parey-Verlag 2005
  • Friedrich T, Lucius R (2005) Konzepte des Parasitismus. In: Allgemeine Parasitologie. Hrsg. T. Hiepe, R. Lucius, B. Gottstein. Parey-Verlag 2005
  • Lucius R (2005) Immunbiologie von Parasiteninfektionen. In: Allgemeine Parasitologie. Hrsg. T. Hiepe, R. Lucius, B. Gottstein. Parey-Verlag 2005
  • Solbach W, Lucius R (2005) Parasite evasion (incl. helminths). In: Topley and Wilson - Microbiology and microbial infections. Immunology Volume, Eds. S. Kaufmann, S. and M. Steward. Edward Arnold Publishers Ltd., London.
  • Miksch G, Bannert B, Lucius R (2004) Parasiten. Überlebenskünstlern auf der Spur. 84 Seiten, Kosmos-Verllag Stuttgart.
  • Hartmann S, Lucius R (2003) Modulation of host immune responses by nematode cystatins. International Journal for Parasitology, Int J Parasitol. 33:1291-302.

 

Bücher
  • Lucius R, Loos-Frank B (2008) Biologie von Parasiten. 552 pages. Springer-Verlag Berlin, Heidelberg, New York.
  • Hiepe T, Lucius R, Gottstein B (Hrsg.) (2005) Allgemeine Parasitologie (mit den Grundzügen der Immunologie, Diagnostik und Bekämpfung). Parey in Medizinverlage Stuttgart GmbH