Humboldt-Universität zu Berlin - Experimentelle Biophysik


Hontani, Y., Broser, M., Silapetere, A., Krause, B.S., Hegemann, P. and Kennis, J.T.K. (2017) The femtosecond-to-second photochemistry of red-shifted fast-closing anion channelrhodopsin PsACR1. Physical Chemistry Chemical Physics 19, 30402-30409. DOI: 10.1039/c7cp06414d!divAbstract


Penzkofer, A., Scheib, U., Stehfest , K., and Hegemann, P. (2017) Absorption and Emission Spectroscopic Investigation of Thermal Dynamics and Photo-Dynamics of the Rhodopsin Domain of the Rhodopsin-Guanylyl Cyclase from the Nematophagous Fungus Catenaria anguillulae. Int. J. Mol. Sci. 18, 2099. doi:10.3390/ijms18102099


Greiner, A., Kelterborn, S., Evers, H., Kreimer, G., Sizova, I., and Hegemann, P. (2017) Targeting of Photoreceptor Genes in Chlamydomonas reinhardtii via Zinc-finger Nucleases and CRISPR/Cas9. Plant Cell 29(10):2498 - 2518. doi:10.1105/tpc.17.00659


Rost, B. R., Schneider-Warme, F., Dietmar Schmitz,D. and Hegemann, P. (2017) Optogenetic Tools for Subcellular Applications in Neuroscience. Neuron 96(3):572-603.


Jonas Wietek, Silvia Rodriguez-Rozada, Janine Tutas, Federico Tenedini, Christiane Grimm, Thomas G. Oertner, Peter Soba, Peter Hegemann & J. Simon Wiegert. (2017) Anion-conducting channelrhodopsins with tuned spectra and modified kinetics engineered for optogenetic manipulation of behavior. Scientific Reports Article number: 14957, Nov. 2017, doi:10.1038/s41598-017-14330-y


Author Correction: Anion-conducting channelrhodopsins with tuned spectra and modified kinetics engineered for optogenetic manipulation of behavior.

Wietek J, Rodriguez-Rozada S, Tutas J, Tenedini F, Grimm C, Oertner TG, Soba P, Hegemann P, Wiegert JS. Sci Rep. 2018 Mar 14;8(1):4765. doi: 10.1038/s41598-018-23001-5.


Kaufmann, J.C.D., Krause, B.S., Grimm, C., Ritter, E., Hegemann, P., and Bartl, F.J. Proton transfer reactions in the red-activatable channelrhodopsin variant. ReaChR. J.Biol.Chem. 292(34):14205-14216, doi: 10.1074/jbc.M117.779629


Luck, M. and Hegemann, P. (2017) The two parallel Photocycles of the Chlamydomonas Sensory Photoreceptor Histidine Kinase Rhodopsin 1. J. Plant Phys. 217:77-84. doi: 10.1016/j.jplph.2017.07.008.


Giliberti V, Badioli M, Nucara A, Calvani P, Ritter E, Puskar L, Aziz EF, Hegemann P, Schade U, Ortolani M, Baldassarre L. (2017) Heterogeneity of the Transmembrane Protein Conformation in Purple Membranes Identified by Infrared Nanospectroscopy. Small 2017 Sep 27. doi: 10.1002/smll.201701181.;jsessionid=2C651FE1C6502E2B3D065004EEE68C09.f03t02


Deisseroth K, Hegemann P. The form and function of channelrhodopsin. Science. 2017 Sep 15;357(6356). pii: eaan5544. doi: 10.1126/science.aan5544. Review. PMID: 28912215


Vierock, J., Grimm, C., Nitzen, N., and Hegemann, P. (2017) Molecular determinants of proton selectivity and gating in the red-light activated channelrhodopsin Chrimson. Sci. Rep. 7(1):9928. doi: 10.1038/s41598-017-09600-8.


Hontani, Y., Marazzi, M., Stehfest, K., Mathes, T., van Stokkum, I.H.M., Elstner, M., Hegemann, P. and Kennis, J.T.M. Reaction dynamics of the chimeric channelrhodopsin C1C2 Sci.Rep. 7(1):7217. doi: 10.1038/s41598-017-07363-w.


Grimm C, Vierock J, Hegemann P, Wietek J.(2017) Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins. J Vis Exp. 2017 May 22;(123). doi: 10.3791/55497.


Krause, B.S., Grimm, C., Kaufmann, J.C.D., Schneider, F., Sakmar, T.P., and Hegemann, P. (2017) Complex Photochemistry within the Green-absorbing Channelrhodopsin ReaChR. Biophys. J. 112, 1166-1175



Hahn F, Mantegazza O, Greiner A, Hegemann P, Eisenhut M, Weber AP. (2017) An Efficient Visual Screen for CRISPR/Cas9 Activity in Arabidopsis thaliana. Front Plant Sci. 24;8:39. doi: 10.3389/fpls.2017.00039. eCollection 2017.