Humboldt-Universität zu Berlin - Mikrobiologie


Junkermeier, E.H., and R. Hengge (2023) Local signaling enhances output specificity of bacterial second messenger signaling networks. microLife 4: uqad026. doi: 10.1093/femsml/uqad026.


Hengge, R.,  M. Pruteanu, J. Stülke, N. Tschowri, and K. Turgay (2023) Recent advances and perspectives in nucleotide second messenger signaling in bacteria. microLife 4: uqad015. doi: 10.1093/femsml/uqad015.


Serra, D. O., & Hengge, R. (2021). Bacterial Multicellularity: The Biology of Escherichia coli Building Large-Scale Biofilm Communities. Annu Rev Microbiol., 75, 269–290.


Hengge R. (2021). High-specificity local and global c-di-GMP signaling. Trends Microbiol., 29(11), 993–1003.


Hengge R. (2020). Linking bacterial growth, survival, and multicellularity - small signaling molecules as triggers and drivers. Curr Opin Microbiol. , 55, 57–66.


Hengge, R. (2019) Targeting Bacterial Biofilms by the Green Tea Polyphenol EGCG. Molecules. 24(13). pii: E2403. doi: 10.3390/molecules24132403.


Hengge, R., S. Häussler, M. Pruteanu, J. Stülke, N. Tschowri, and K. Turgay (2019) Recent Advances and Current Trends in Nucleotide Second Messenger Signaling in Bacteria. J. Mol. Biol. 431(5):908-927. doi: 10.1016/j.jmb.2019.01.014.


Serra, D.O., and R. Hengge (2017) Experimental detection and visualization of the extracellular matrix in macrocolony biofilms. Methods Mol. Biol. 1657: 133-145. doi: 10.1007/978-1-4939-7240-1_11.


Hengge, R. (2016) Trigger phosphodiesterases as a novel class of c-di-GMP effector proteins. Phil. Trans. R. Soc. B 371: 20150498, doi:


Hengge, R., A. Gründling, U. Jenal, R. Ryan, and F. Yildiz (2015) Bacterial signal transduction by c-di-GMP and other nucleotide second messengers. J. Bacteriol. 198: 15-26.  doi: 10.1128/JB.00331-15.


Hengge. R. (2015) Bakterielle Megastädte - 3D-Architektur von Biofilmen. Biospektrum 21(5): 480-483.


Mika, F., and R. Hengge (2014) Small RNAs in the control of RpoS, CsgD and biofilm functions in Escherichia coli. RNA Biol. 11: 494-507. doi: 10.4161/rna.28867.


Serra, D.O., and R. Hengge (2014) Stress responses go three-dimensional - the spatial order of physiological differentiation in bacterial macrocolony biofilms. Environ. Microbiol. 16, 1455-1471. doi: 10.1111/1462-2920.12483.


Hengge, R., and V. Sourjik (2013) Bacterial Regulatory Networks – from self-organizing molecules to cell shape and community patterns. EMBO Rep. 14, 667-669. doi: 10.1038/embor.2013.93.


Mika, F., and R. Hengge (2013) Small regulatory RNAs in the control of motility and biofilm formation of Escherichia coli and Salmonella. Int. J. Mol. Sci. 14, 4560-4579. doi:10.3390/ijms14034560.


Hengge, R. (2013) Novel tricks played by the second messenger c-di-GMP in bacterial biofilm formation. EMBO J. 32, 322-323. doi: 10.1038/emboj.2012.351.


Karch, H., E. Denamur, U. Dobrindt, B.B. Finlay, R. Hengge, L. Johannes, E.Z. Ron, T. Tønjum, P.J. Sansonetti, and M. Vicente (2012) The enemy within us: lessons from the 2011 European Escherichia coli O104:H4 outbreak. EMBO Mol. Medicine 4, 841-848.


Povolotsky, T.L., and R. Hengge (2012) ‘Life-style’ control networks in Escherichia coli: Signaling by the second messenger cyclic-di-GMP. J. Biotechnol. 160, 10-16.


Hengge, R. (2011) Stationary phase gene regulation in Escherichia coli. Chapter 5.6.3. in: EcoSal – Escherichia coli and Salmonella: Cellular and Molecular Biology (A. Böck, R. Curtiss III, J.B. Kaper, P.D. Karp, F.C. Neidhardt, J.M. Slauch, and C.L. Squires, eds.). ASM Press, Washington, DC. doi: 10.1128/ecosal.5.6.3


Hengge, R. (2010) Cyclic-di-GMP reaches out into the bacterial RNA world. Sci. Signal. 3, pe44.


Hengge, R. (2009) Proteolysis of σs (RpoS) and the general stress response in Escherichia coli. Res. Microbiol. 160, 667-676.


Hengge, R., and K. Turgay (2009) Proteolysis in prokaryotes – from molecular machines to a systems perspective. Res. Microbiol. 160, 615-617.


Pesavento, C., and R. Hengge (2009) Nucleotide-based second messengers in bacteria. Curr. Op. Microbiol. 12, 170-176.


Hengge, R. (2009) Principles of cyclic-di-GMP signaling. Nature Rev. Microbiol. 7, 263-273.


Hengge, R. (2008) The two-component network and the general stress sigma factor RpoS (σs) in Escherichia coli. Adv. Exp. Med. Biol. 631, 40-53.


Klauck, E., A. Typas, and R. Hengge (2007) The σs subunit of RNA polymerase as a signal integrator and network master regulator in the general stress response in Escherichia coli Sci. Progr. 90, 103-127.


Typas, A., G. Becker, and R. Hengge (2007) The molecular basis of selective promoter activation by the σs subunit of RNA polymerase. Mol. Microbiol. 63, 1296-1306.


Klauck, E., G. Becker, and R. Hengge (2005) Proteolyse als Regulationsprinzip in Prokaryonten. Biospektrum 11, 166-168.


Hengge. R., and R.L. Gourse (2004) Tying together the cellular regulatory network. Curr. Op. Microbiol. 7, 99-102.


Weichart, D., and R. Hengge (2003) Physiologische Flexibilität durch regulierten Proteinabbau: Neue Dimensionen der Stressanpassung in Bakterien. BIOforum 11, 722-723.


Hengge, R., and B. Bukau (2003) Proteolysis in prokaryotes: protein quality control and regulatory principles. Mol. Microbiol. 49, 1451-1462.


Jenal, U. and R. Hengge-Aronis (2003) Regulation by proteolysis in bacteria. Curr. Op. Microbiol. 6, 163-172.


Hengge-Aronis, R. (2002) Stationary phase gene regulation: what makes an Escherichia coli promoter σs-selective? Curr. Op. Microbiol. 5, 591-595


Hengge-Aronis, R. (2002) Signal transduction and regulatory mechanisms in the control of the σs (RpoS) subunit of RNA polymerase. Microbiol. Molec. Biol. Rev. 66, 373-395.


Hengge-Aronis, R. (2002) Recent insights into the general stress response regulatory network in Escherichia coli. J. Mol. Microbiol. Biotechn. 4, 341-346.


Hengge-Aronis, R. (1999) Interplay of global regulators and physiology in the general stress response in Escherichia coli. Curr. Op. Microbiol. 2, 148-152.


Hengge-Aronis, R. (1996) Back to log phase: σs as a global regulator in the osmotic control of gene expression in Escherichia coli. Mol. Microbiol. 21, 887-893.


Loewen, P., and R. Hengge-Aronis (1994) The role of the alternative sigma factor σs in bacterial global gene regulation. Ann. Rev. Microbiol. 48, 53-80.


Hengge-Aronis, R. (1993) Survival of hunger and stress: the role of rpoS in early stationary phase gene regulation in E.coli. Cell 72, 165-168.


Hengge, R. and W. Boos (1983) Maltose and lactose transport in Escherichia coli: Examples of two different types of concentrative transport systems. Biochim. Biophys. Acta 737, 443-478